Pelvic inflammatory disease PID could be a useful marker for gynecological cancers. Thus, we designed a large-scale, nationwide, controlled cohort study to investigate whether PID or other risk factors increased the risk of second primary cancers in patients with cervical cancer treated by surgery alone.
Patients who received definite surgery were selected. To exclude the effect on second primary malignancy by treatment modalities, all cervical patients who ever having received adjuvant or definite radiotherapy or chemotherapy for primary cervical cancer were excluded. Finally, cervical cancer patients treated by surgery alone without adjuvant treatments were analyzed.
Cox proportional hazards model was used for multivariate analysis and the Kaplan-Meier method was used to assess the cumulative risks. Regarding the incidence of second primary cancers, the standardized incidence ratio SIR was used. The median follow-up time was The 6-year cumulative risk of second primary cancers is 0. After adjustment for confounders, age of less than 50 years, the presence of diabetes mellitus, and PID were significantly positivity associated with the risk of second primary cancers.
A higher incidence of second primary cancers was observed in the genitals, bladder, and colon. In conclusion, the incidence of second primary cancers was higher in the genitals, bladder, and colon in patients with cervical cancer treated with surgery alone. The patients with PID had a higher risk of second primary cancers. Related: Cervical Cancer.
Signet ring cell carcinoma of resectable metastatic colorectal cancer has rare surgical value. The aims are to investigate the value of resection in patients with resectable metastatic signet ring cell colorectal cancer. Kaplan-Meier and COX models were used to analyze the differences in the survival. Logistic regression models were used to evaluate the relationship between SRCC and other clinicopathological factors.
Related: Colorectal Bowel Cancer. Statin use and risk of endometrial cancer: a nationwide registry-based case-control study. Acta Obstet Gynecol Scand. In a nationwide registry-based case-control study, we examined the association between statin use and risk of endometrial cancer. Ever use of statin was defined as two or more prescriptions on separate dates.
The multivariable-adjusted models included parity, hormone replacement therapy HRT , obesity, diabetes, chronic obstructive pulmonary disease and education. We evaluated whether the association between statin use and endometrial cancer varied with duration and intensity of statin use, type of endometrial cancer or patient characteristics. We observed no association between ever use of statins and endometrial cancer risk OR 1. In addition, endometrial cancer risk did not vary substantially with duration or intensity of statin use.
Stratification by type of endometrial cancer also yielded neutral ORs. Occupation and mesothelioma in Sweden: updated incidence in men and women in the 27 years after the asbestos ban. Epidemiol Health. Data from this cohort were linked to the population-based Swedish Cancer Registry and Swedish Total Population Registry for three periods between and , and then further linked to the Swedish NOCCA job-exposure matrix, which includes 25 carcinogenic substances and the corresponding exposure levels for occupations.
Multivariate analysis was used to calculate standardized incidence ratios SIRs for mesothelioma of the peritoneum and pleura by gender, occupational category, carcinogenic substance, and for multiple occupational exposures simultaneously. We found a significantly increased risk of mesothelioma in 24 occupations, as well as clear differences between the genders. Among men, increased risks of mesothelioma of the pleura were observed in male-dominated occupations, with the greatest elevation of risk among plumbers SIR, 4.
Among women, increased risks were observed in sewing workers, canning workers, packers, cleaners, and postal workers. In multivariate analysis controlling for multiple occupational exposures, significant associations were only observed between asbestos exposure and mesothelioma. The asbestos ban of has yet to show any clear effect on the occurrence of mesothelioma in this cohort. Among women, the occupations of canning workers and cleaners showed increased risks of mesothelioma of the pleura without evidence of asbestos exposure.
The frontline of esophageal cancer treatment: questions to be asked and answered
Related: Mesothelioma. The temporal and age-dependent patterns of hysterectomy-corrected cervical cancer incidence rates in Denmark: a population-based cohort study. As only women with an intact cervix are at risk of cervical cancer, failing to remove hysterectomized women from the denominator may underestimate the cervical cancer incidence. We aimed to describe the temporal and age-dependent patterns of cervical cancer incidence in Denmark before and after correction for hysterectomy.
Hysterectomy-corrected rates were calculated by subtracting post-hysterectomy person-years from the denominator. After correction for hysterectomy, the rate increased by 8. The highest uncorrected incidence was seen in women aged years, peaking at Role of reduced-intensity conditioning allogeneic hematopoietic cell transplantation in older patients with de novo acute myeloid leukemia.
Cancer Registries | CancerIndex
Reduced-intensity conditioning RIC regimens extend the therapeutic use of allogeneic hematopoietic cell transplantation HCT to older patients. J Cancer Res Clin Oncol. While cases are rising, data concerning effective management are limited. The present paper sought to elucidate the epidemiology and prognosis of RM, while also analyzing the role of adjuvant radiation therapy RT.
Ways To Give
Patients 18 or older with non-metastatic disease who had undergone surgery were included. Data regarding the age, race, sex, marital status, stage, and radiation sequence with surgery were extracted from the database and analyzed. RM is significantly more common in whites compared to nonwhites and occurs equally in males and females. Most patients are diagnosed at an early stage. RT does not improve survival, regardless of stage. Optimal management of this lethal disease remains to be elucidated. Related: Melanoma. Detection of human papillomavirus DNA in archived clinical samples of breast and lung cancer patients from North Pakistan.
It has also been associated with some non-genital cancers. A subset of oropharyngeal cancers are known to be caused by HPV. Its aetiological involvement has been suggested for breast and lung cancer as well. Related: Breast Cancer Lung Cancer. Incidence of neuroepithelial primary brain tumors among adult population of Emilia-Romagna Region, Italy. Neurol Sci. This study is the largest in Southern Europe. Specialists in neurosurgery, neurology, neuroradiology, oncology, radiotherapy, genetics, and pathology of ER notified all suspected nPBT adult cases residing in ER 4,, inhabitants observed during Furthermore, through ICD-9 discharge codes, we identified and reviewed all possible cases.
Neuroepithelial PBT diagnosis was based on histological or radiological findings. These latter were significantly older. The standardized incidence was It was 9. Health disparities and impact on outcomes in children with primary central nervous system solid tumors. J Neurosurg Pediatr. However, there have been few reports assessing how health disparities impact pediatric patients with malignancies.
Geocoded information was used to calculate the driving distance between a patient's home and the nearest pediatric cancer treatment center. Logistic regression was used to determine factors associated with advanced-stage disease.
Survival probability and hazard ratios were calculated using life table methods and Cox regression. Distance to treatment and SES did not impact disease stage at presentation in the adjusted analysis.